I created this Super Antihistamine Smoothie to fill the gap of tasty, low histamine smoothies that actually support your body. Packed with cherries, blueberries, moringa, and pea sprouts, each ingredient is chosen for its natural antihistamine properties. It’s a quick, nutrient-rich drink that helps calm digestion and balance histamine levels while tasting delicious.
If you’re looking for more refreshing vegan smoothies, try my blueberry cucumber smoothie and mango moringa smoothie.

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✔️ Why This Recipe is Great
Helps Clear Histamine. Eating foods with antihistamine properties is one of the best ways to clear histamine naturally, and each of these ingredients plays a different role in staving off histamine toxicity. Check out the low histamine foods list for more info on which foods to keep in your diet if you're experiencing symptoms of histamine intolerance.
Calming on the Stomach. As you may have read in recent posts, I'm currently trying to heal from an ulcer, and drinking a smoothie with greens as one of my two daily meals has been part of that process.
Packed With Antihistamine Foods. I've formulated this particular recipe to help keep my stomach happy and balance out any lingering histamine from the previous meal, as the pea sprouts in this recipe contain DAO. All of the other ingredients are actively antihistamine foods (water notwithstanding!).
🍎 Ingredients

Cherries (Fresh or Frozen): these are the base of your smoothie, and they're a great source of antioxidants and antihistamine plant chemicals.
Frozen Blueberries: these bright berries are an antioxidant and antihistamine powerhouse! Making smoothies with frozen blueberries doesn't have to dilute their power, either. Just be sure to use organic, locally-sourced blueberries when possible.
Apple: a small apple is the best approach to this smoothie, but you could also use half of a large apple. Since the skins of the apples contain an abundance of histamine-fighting nutrients, I like to leave those on, but you can peel them off. I used a fuji apple because I like the balance of crisp and sweet, but you can use any variety.
Fresh Ginger: possibly the best-known low histamine spice, ginger is the sharp, mildly sweet root of a flower; it’s been used for thousands of years in beverages both sweet and savory.
Pea Sprouts: these sprouts are a vegan source of DAO, and add a mild grassy flavor tot the smoothie, so use sparingly.
Moringa: while you'll only use a bit of this, it adds a lot of extra antihistamine power.
See recipe card for exact ingredients and quantities.
🥤 How to Make Antihistamine Smoothie (Step-by-Step)
Step 1) Measure out all your ingredients and put them into the blender (image 1).

Step 2) Blend everything together for about 1 minute (image 2) & serve!
🥥 Variations
- Cherry-Only Antihistamine Smoothie: Skip the blueberries and increase the frozen cherries slightly for a simpler, often better-tolerated low histamine option.
- Blueberry-Forward Smoothie: Reduce the cherries and use more blueberries, which many find gentler on a low histamine diet.
- Creamier Smoothie: Add a bit more coconut milk or use full-fat coconut milk for a richer, more filling texture.
- Ginger-Free Version: Omit the ginger entirely for a milder flavor if ginger is a personal trigger.
- Extra Green Boost: Increase the pea sprouts or add a small amount of fresh lettuce for more greens without raising histamine.
- Less Sweet Smoothie: Reduce or omit the monk fruit powder and rely on the natural sweetness of the fruit.
- Anti-Inflammatory Focus: Slightly increase the turmeric (if well tolerated) for added anti-inflammatory support while staying low histamine.
🧊 Freezing
If you're not eating low histamine, you can refrigerate this smoothie with for up to 72 hours, though after about two days it may become a bit soggy and any textural cherries and blueberries will soften. For a freezer smoothie, you can keep this frozen for up to 3 months without losing any of its nutritional value.
👨🏻🍳 Expert Notes & Tips
Swapping Fruits. You can use equal amounts of any other berries in place of the cherries and blueberries, but be careful to balance out the flavor profiles of all the ingredients.
❓ What to Serve With Antihistamine Smoothie
🙋 Frequently Asked Questions
Cherries and blueberries contain natural compounds that may help support antihistamine and anti-inflammatory pathways.
Yes, this recipe is already 100% vegan when using coconut milk or another plant-based milk.
Absolutely. Both spices are optional and can be reduced or omitted if they’re not well tolerated.
Moringa is often used for its anti-inflammatory properties, but tolerance varies—start with a small amount.
No refined sugar is added; sweetness comes from fruit and a small amount of monk fruit powder.
📖 Recipe

Cherry Antihistamine Smoothie (Low Sugar)
Equipment
- Blender
Ingredients
- 2 cups frozen cherries ~10 oz.
- ½ cup frozen blueberries
- 1 small apple cut into pieces
- ½ cup coconut milk or other tolerated milk
- 1 teaspoon fresh or frozen ginger ~1"
- 1 large handful pea sprouts
- ½ teaspoon moringa
- ¼ teaspoon turmeric
- ⅛ teaspoon monk fruit powder
- ⅛ teaspoon of salt
Instructions
- Measure out all your ingredients and put them into the blender.
- Blend everything together for about 1 minute & serve!
Notes
Nutrition
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Amanda says
To clarify, does this use pea sprouts or pea microgreens, and do you include the peas themselves or just the greens? Either way, do you have a good recommendation for where to source the peas to sprout?
Thanks so much for this!
Max says
Amanda,
You can use either, though I prefer pea sprouts, as shoots are just a bit older and therefore less concentrated in DAO. I do not use whole peas, as once they've grown into peas, they do have some detectable histamine which can bother many people. In fact, greens peas are generally considered high histamine. But I do thankfully have a source for pea sprouts at my local Farmer's market, however for a yearround source, you can quite easily buy seeds and grow your own. It's surprisingly easy, and can supply you for several weeks!
Pam says
I have just discovered your site! It has so much information. Thank you!
What would you recommend as a protein supplement for smoothies?
I had read that vitamin C helps.....which brand would you recommend or just keep getting it thru foods?
Have you ever considered compiling all your knowledge into book form?
Max says
Hi, Pam! It's my pleasure; I'm glad you've found it helpful. 🙂
I'm not a doctor, but from my experience & studies, seed-derived protein powders like hemp, sunflower, or pumpkin seed proteins will be lowest in histamine. Vitamin C is abundant in berries, so rather than adding a supplement you may or may not tolerate, I'd use fresh fruits and veggies high in vitamin C.
It's something I've thought about once I finish my Master's in Nutrition, but between school, work, the site, and wedding planning, I just don't have the bandwidth to bring everything together in book form at the moment. Hopefully one day soon, though!
Will says
Really helpfull for the many people who are totally unaware of methylation issues and the v677t implications it can and does ruin peoples lives and marriages because of ongoinf chronic symptoms of Mast cell and histamine issues
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i send my patients to this site
Max says
Yeah, being chronically low-energy or in pain or anxious can be super draining, and it makes you frustrated and exhausted in ways you couldn't have imagined before. I can't bear to think of what that could do to a marriage! That name sounds familiar; I'll have to give him a look. Many thanks!